NIPERA INC

2-2600-110214-00 ni metal cell uptakenew occupational exposure limit values (oelvs) for both the inhalable and respirable fraction for nickel compounds were adopted by the european union in march 2022. They are aligned with the scientific opinion of nipera and are health-protective and achievable for industry. The oelvs are currently being transposed into national regulations and will enter into force in 2025. The nickel institute will continue to monitor transposition into national law. Norway is debating its transposition approach, and nipera has provided comments to the norwegian labour inspection authority in q3 of 2023. Additionally, nipera toxicologists and the nickel institute's industrial hygienist have met virtually with toxicologists assigned by the federation of norwegian industries to bring them up to speed on the state of nickel inhalation science and, in particular, the importance of the threshold for effects.

2-2600-238300-00 meeting of the ecotoxicity technical advisory panel (etap)

2-2600-210105-00 review of health effects of ni in ambient airnickel and nickel compounds are targets for regulatory scrutiny because of their health and environmental classifications. An example of this occurred in october 2024 when the us agency for toxic substances and disease registry (atsdr) released a final version of its toxicological profile (tox profile) of nickel. Atsdr profiles are influential as reference documents for regulators and researchers globally. , atsdr included a new mrl of 3 ng ni/m, a very low level that is well below standards elsewhere in the world and, in fact, is so low that it is in the range of natural ambient air nickel levels in areas of the us. Nipera plans to communicate the errors and procedural concerns to atsdr as soon as possible in 2025 and may also consider publishing an alternative approach to deriving mrls in the peer reviewed literature.