CHILDREN'S RESEARCH INSTITUTE

Center for cancer and immunology research - see schedule o.program service activity 3center for cancer and immunology research: the center for cancer & immunology research (ccir) aims to develop and apply scientific knowledge in the areas of cancer, blood, and infectious and immunologic disorders to advance patient care. The ccir was reorganized to integrate the clinical and research enterprises in oncology, infectious disease, hematology, allergy, immunology and rheumatology in order to be aligned with the center for cancer and blood disorders (ccbd) and promote and facilitate the conduct of translational research. This reorganization has now resulted in the establishment of 5 sections:1. Childhood cancer2. Infectious disease3. Cancer immunology/immunotherapy4. Hematology & transfusion medicine 5. Allergy, immunology, rheumatologythe new structure has allowed the ccir leadership to work closely with ccbd leadership to better develop a strategic goal for the future, including strategic expansion of research programs rather than opportunistic recruitments. The center of cancer and immunology research had $22,706,348 in expenses fy 2024.

Center for genetic medicine research: the center for genetic medicine research researches, diagnoses, and treats genetic disorders-diseases and conditions in children that are caused by inherited genes that do not function normally. Founded in 1999, the center emphasizes translational research (bench-to-bedside) and harnesses emerging technologies for genetic and proteomic analysis.researchers at the center for genetic medicine research conduct basic and clinical research into some of childhood's most well-known genetic disorders, including asthma and lung disease, diabetes, inborn errors of metabolism, macular degeneration, muscular dystrophies, sickle cell disease, obesity & metabolic syndrome and white matter disease. Almost all of the center's programs combine basic, clinical, and/or community research, including studies of: muscle physiology, genetics, & metabolism and duchenne muscular dystrophy. The center for genetic medicine research had $18,440,934 in expenses fy 2024.sheikh zayed institute (szi) for pediatric surgical innovation:launched in september 2009, the research space officially opened in april 2011. The sheikh zayed institute for pediatric surgical innovation at children's national redefines what is possible in surgery for children by combining research and clinical expertise into one collaborative team. The institute develops knowledge, tools, and procedures that benefit children in the washington dc region, across the country, and around the world. The primary focus is to learn from today's surgeries and conduct innovative research based on that knowledge to improve pediatric surgery for children. Each year the szi faculty publish over 90 peer reviewed articles in top ranked journals, more than 50 new patents have filed to date, and more than 10 startup companies have been established. All faculty at the szi now hold nationally recognized peer reviewed funding. The szi hosts the national capital consortium for pediatric devices innovation, an fda funded program (one of the 8 in the country), to support pediatric focused product development and advocacy. The sheikh zayed institute for pediatric surgical innovation had $14,205,678 in expenses fy 2024.total other programs: